Snakes, spiders and scorpions are some of the most lethal animals on the planet, producing venoms either as part of a defence mechanism towards predators, or as a means to subdue and kill their prey for food. For millions of years, spider and scorpion venoms have evolved to disable the central nervous system of insects. In contrast, most snake venoms target the circulatory system of vertebrates, resulting in uncontrolled bleeding and organ failure. And yet, ironically, the properties that make venoms deadly are the same properties that can be used for lifesaving medicines or analgesics.
Venomous animals have evolved a vast array of peptide toxins for prey capture and defence. These peptides are directed against a wide variety of pharmacological targets, making them an invaluable source of ligands for studying the properties of these targets in different experimental paradigms. A number of these peptides have been used in vivo for proof-of-concept studies, with several having undergone preclinical or clinical development for the treatment of pain, diabetes, multiple sclerosis and cardiovascular diseases.
Xegate owns two cutting edge laboratories to produce poisons of highest quality and purity and three farms for breed various kinds of poisonous animals, using the most innovative methods.
Watch here a video taken in our laboratories:
Xegate exploits the world’s most advanced techniques to meet the most stringent European and American standards Xegate, in partnership with Shirosh, is ready to cooperate with the world’s top notch Companies to support the world of special medications.CLICK HERE TO DOWNLOAD OUR BROCHURE
Our production includes rare animals as follows:
- Saw scaled viper (Echis) – 200 gr of venom produced per month
- West Asian blunt nosed viper – 200 gr / month
- Central Asian cobra (Naja oxiana) – 200 gr / month
- Persian horned viper (Pseudocerastes persicus fieldi) – 200 gr / month
- Spider tailed horned viper (Pseudocerastes) – 30 gr / month
- Desert horned viper (Cerastes gasperettii) – 30 gr / month
- Caucasian pit viper (Gloydius intermedius) – 100 gr / month
- Latifis viper (Vipera latifii martens) – 20 gr /month
- Zigzag mountain viper (Vipera albicornuta) – 20 gr /month
- Vipera raddei kurdestanica – 20 gr / month
- Mahons viper (Eristicophis macmahoni) – 10 gr /month
- Black widow spider (Latrodectus) – 5 gr /month
- White widow spider (Latrodectus pallidus) – 5 gr / month
- Lesser Asian scorpion (Mesobuthus epeus) – 100 gr / month
- Fat tailed scorpion (Androctonus crassicauda) – 100 gr /month
- Hemiscorpius lepturus – 100gr / month
- Odonthobuthus doriae – 100 gr / month
- Hottentotta sailcyi – 1 liter / month
- Hottentotta jayakari – 500 gr /month
For every species, we milk every day 3 grams of venom from around 3,000 animals of the same species.
Before entering a farm, each animal is put in a quarantine area to preserve the other species.
The feed of the animals follows a precise feeding cycle and the animals are kept is save rooms at controlled temperature and humidity to preserve the quality of their precious venom.
We keep track of any animal and do not mix them to preserve venom’s purity.
Right after milikng the venom is immediately stored in vacuum and put at -196°C by liquid nitrogen.
As, if the venom is kept in open air it decays in 15 minutes (proteins and enzymes can no more be exploited).
Or, alternatively, we store the venom as a powder and it lasts more than 5 years.
We produce natural venom (purity around 65%) or pure venom (purity 95%). For proteins and enzymes can be stored in powder only.
Before storage and shipment the venom is analyzed.
Venoms can be produced according to Client’s datasheet.
The venom can be used mainly for:
- Anticancer drugs (liquid venom of scorpions, in nitrogen)
- Surgical purposes and painkillers (liquid venom of snakes, in nitrogen)
- Brain cancer drug (liquid venom of spider, in nitrogen)
- Antivenom (dried venom)
- Pure proteins (in powder)
Farm of scorpion breeding and extract on of scorpion venom in the past animals were used for transportation, nutrition, art affairs, symbolism and metaphysics.
Nowadays with the development of science and technology, alive creatures are used for industry, manufacturing and also in production of drugs and medicines.